All Training Faculty
Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.
Mechanisms of neuromodulation in central neurons
Circuit mechanisms of sleep and epilepsy
Molecular mechanisms linking inflammation and insulin signaling to control cell growth and metabolism
Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders
Epigenetic and genetic mechanisms underlying metabolic disease
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer
The Neurobiology of Energy Balance
Systems Genetics Approaches to Understand Cardiometabolic Traits
Biophysical Chemistry: Membrane protein structure, function, and dynamics
Cellular and molecular mechanisms of Neisserial pathogenesis
Elucidating and Understanding the Mechanisms Underlying Nervous System Development
Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis
The Role of Diabetes in Cognitive Decline
Exploring new therapeutics avenues to treat Multiple Sclerosis.
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Neural control of blood pressure and respiration
Molecular mechanisms controlling insulin signaling and fat synthesis.
Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry
Translating our discoveries in the microcirculation to tangible benefits in patients.
Systems-biology approaches to cancer biology and virology.
Lung injury and repair, sepsis
Advancement in the design of imaging agents; molecular imaging and radiological sciences.
Nanotechnologies for targeted drug delivery
Mechanisms of Chemotherapy Resistance in Ovarian and Other Gynecologic Malignancies
The mechanism of action of small molecules and the fundamental biological role of protein tyrosine phosphatases
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Composition, Biophysics and Physiology of Cellular Membranes
Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)
Chemical biology of sphingosine 1-phosphate
Behavioral Pharmacology, Sex Differences, Animal Models of Addiction
Immune System Regulation of Cardiometabolic Disease
Structure-Function of Active Transporters
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.
Apoptotic cell clearance mechanisms in health and disease
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery
Investigation of the neuronal circuits and epigenetic modifications involved in the control of food intake, impulsivity and novelty seeking behavior
Transcriptional Silencing and Aging in Yeast
Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension
Tailored fit targeting approaches: Cancer Immunotherapy, Antibodies and conjugates
Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.
Molecular and Signaling Mechanisms of Skeletal Muscle Plasticity
Neural Circuits in Healthy and Diseased Brains
Early detection, cancer prevention, and tumor microenvironment