Diabetes and Insulin Action
Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.
Mechanisms of neuromodulation in central neurons
Circuit mechanisms of sleep and epilepsy
Molecular mechanisms linking inflammation and insulin signaling to control cell growth and metabolism
T Lymphocyte Responses To Virus Infection
Protein Phosphorylation in Cell Signaling
Structural and Functional Basis for Oncogenesis; Targeted Drug Development; Structural Studies of Membrane Proteins
Biophysical Chemistry: Membrane protein structure, function, and dynamics
Regeneration and Developmental Biology of the Hearing and Balance Organs in the Vertebrate Ear.
Cellular and molecular mechanisms of Neisserial pathogenesis
Electrical signals in inflammation and immunity
Genomic Instability in Cancer Cells; Noncoding RNAs in differentiation and cancer
Exploring new therapeutics avenues to cure Multiple Sclerosis.
Hematopathology and Understanding the Molecular Basis of Hematopoiesis and Leukemogenesis
Neural control of blood pressure and respiration
Molecular mechanisms controlling insulin signaling and fat synthesis.
Immune regulation for HCV infection and chronic liver inflammation
Lipid Metabolism in Inflammation and Immunity
Intercellular communication as it relates to blood pressure regulation
Systems-biology approaches to cancer biology and virology.
Lung injury and repair, sepsis
Advancement in the design of imaging agents; molecular imaging and radiological sciences.
Nanotechnologies for targeted drug delivery
Neuroimmunology and glia biology in cognition, neurodevelopment and neurodegeneration
Mechanisms of Chemotherapy Resistance in Ovarian and Other Gynecologic Malignancies
The mechanism of action of small molecules and the fundamental biological role of protein tyrosine phosphatases
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Chemical biology of sphingosine 1-phosphate
Atherosclerosis, Obesity, Diabetes
Structure-Function of Active Transporters
Epigenetic Control of Perivascular and Stem Cell Plasticity/Trans-Differentiation during Injury-Repair and in Disease
Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies
Exploring epilepsy circuits then preventing seizures using AAV-based gene therapies.
Apoptotic cell clearance mechanisms in health and disease
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism, atherosclerosis, Small molecule approaches to drug discovery
Investigation of the neuronal circuits and epigenetic modifications involved in the control of food and drug reward
Hypothalamic Peptide and Steroid Regulation of Pituitary Gene Transcription; Estrogen Action in Neuroendocrine and Reproductive Tissues; Estrogen Action in Breast Cancer
Pharmacology and function of T-type (low-voltage-activated, LVA) calcium channels in sensory transmission.
Molecular and Signaling Mechanisms of Skeletal Muscle Plasticity
Cardiac Gap Junction Membrane Channels / Integrins Water Channels / Rotavirus / Reovirus / Retrovirus
Neural Circuits in Healthy and Diseased Brains
Mouse models of brain cancers