Research Staff

Yu-Hsin (Eva) Chu, Ph.D.

Research Associate
Bayliss Lab, Pinn 5013

email: yc6p@virginia.edu
phone: 434-982-4466

I am interested in elucidating the regulatory mechanism of membrane proteins, especially trafficking and gating kinetics of ion channels. Currently, I focus on understanding the regulation of an ATP-releasing channel, Pannexin 1, in particular its activation by caspase-mediated cleavage and by receptor-induced signaling cascades.

M. Murat Koseoglu, PhD

Senior Scientist
Lazo Lab, MR4 4084

email: mmk9f@virginia.edu
phone: 434-243-1648

Aberrant neuronal cell cycle re-entry precedes and mechanistically prompts most of the neuronal loss observed in Alzheimer’s disease (AD). At Lazo lab, we are using human IPS derived neurons to develop a high content screen to find pharmaceutically attractive small molecules that will inhibit aberrant neuronal cell cycle re-entry in AD.

Keyong Li

Keyong Li, Ph.D.

Research Associate
Bayliss Lab, Pinn 5013

email: kl4jd@virginia.edu
phone: 434-982-4466

My current study is how central chemoreceptors modulate respiration when exposed to high CO2 or the pH changed in blood in development. Phox2b (+) neurons in Retrotrapezoid Nucleus (RTN) are intrinsically sensitive to pH and play a vital role in regulating respiration. My study is focusing on the developmental changes of their pH-sensitivity and excitability. Multiple techniques including patch clamp, PCR, immunohistochemistry, imaging are used to investigate the ion channels in RTN neurons which are contributing to the developmental changes from cellular level to molecular level. Finally, the identified ion channels will be tested in whole animal model using in vivo gene transfer. The goal is to illuminate the mechanisms of modulation neuronal excitability and of respiration in development.

Sudip Pandit, PhD

Research Associate
Zhu Lab, Pinn Hall 5025

email: sp4sj@virginia.edu
phone: 434-243-9562

I am mainly interested in identifying the cortical interneurons in layer 6 and their circuit. With the help octuple patch clamp recording, immunohistochemistry and neurolucida technique, we try to match the physiology and anatomy of the neurons. We classify the neurons based on various

George M.P.R. Souza, PhD

Research Associate
Guyenet Lab, Pinn Hall 5228

email: gs4bd@virginia.edu
phone: 434-227-6010

My research interest is related to neural control of breathing and blood pressure. We are investigating how neurons at the lower brainstem (retrotrapezoid nucleus and rostral ventrolateral medulla) regulate breathing, blood gases homeostasis, blood pressure and arousal. We use chemo- and optogenetic approaches in vivo to perform gain- or loss-of-function experiments in order to reveal the role of specific neuronal types in those physiological variables.

Peng Zhang

Research Associate
Zhu Lab, Pinn Hall 5025

email: pz8g@virginia.edu
phone: 434-243-9562

I am interested in elucidating how the different neurotransmitters are regulated under physiological and pathological conditions. My current project mainly focuses on developing genetically encoded sensors to detect acetylcholine and serotonin (5-HT).