Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.
Mechanisms of neuromodulation in central neurons
Circuit mechanisms of sleep and epilepsy
Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis
Neural control of blood pressure and respiration
Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.
Neural Circuits in Healthy and Diseased Brains
Other PSTG Faculty
Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension