UVA Researchers, led by Jonathan Kipnis, PhD, have found a way to impede the development of multiple sclerosis in mice by targeting the lymphatic vessels surrounding the brain. These findings were published in, Nature:
Antoine Louveau, Jasmin Herz, Maria Nordheim Alme, Andrea Francesca Salvador, Michael Q. Dong, Kenneth E. Viar, Grace Herod, James Knopp, Joshua C. Setliff, Alexander L. Lupi, Sandro Da Mesquita, Elizabeth L. Frost, Alban Gaultier, Tajie H. Harris, Rui Cao, Song Hu, John R. Lukens, Igor Smirnov, Christopher C. Overall, Guillermo Oliver, and Jonathan Kipnis (2018). CNS lypmpathic drainage and neuroinflammation are regulated by meningeal lympathic vasculature. Nature Neuroscience, 1526-1726
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Dr. Kipnis is a PSTG preceptor for Pharmacology, the Harrison Distinguished Teaching Professor and Chair of the department of Neuroscience and the Director of the Center for Brain Immunology and Glia (BIG).