Bayliss Lab

The Bayliss Lab as part of the Department of Pharmacology,  investigates the following research areas:

  1. Central respiratory chemosensitivity: cellular sensors and molecular detectors.
  2. Potassium leak channels: molecular basis, mechanisms of modulation and physiological roles.
  3. Pannexin channels: reversible and irreversible mechanisms of activation.
  4. Mechanisms of anesthesia: molecular targets, neural substrates and clinical endpoints.
Human brain model with blue glow, studio shot

Receptor in the Brain Controls Breathing

Control of breathing in mammals depends primarily not on sensing oxygen, but rather on detecting concentrations of carbon dioxide in the blood.
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four chains linked at a common point

Unexpected Link Between an Antibiotic, Pannexin Channels, and Apoptosis

A novel linkage between an antibiotic, pannexin channels, and cellular integrity.
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Man with white coat and hair net looking into a microscope

Identification of a Novel Mitochondrial Uncoupler That Does Not Depolarize the Plasma Membrane

The pharmacological uncoupling for the treatment of the myriad of diseases that are associated with altered mitochondrial function.
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