Fiske Drug Discovery Laboratory

The Fiske Drug Discovery Laboratory is the home of the Lazo Lab (LazoLand) and the Sharlow Lab (Sharlowville). The primary research focus of the Lazo Laboratory is on the mechanism of action and of resistance to novel and existing anticancer agents. The Sharlow Lab’s research focuses on exploiting chemical biology approaches to understand signaling pathways that are critical for parasite, neuronal and tumor cell viability.

 

Publications

Find out more about our research in our recently published articles and publications.

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Refining Radiation for the Next Century

About half of all the patients today with cancer are treated with radiotherapy and it remains one of our most effective treatment modalities. The use of altered fractionation schedules and image-guided radiotherapy has significantly improved patient outcomes.
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Pathological Confluence of Alzheimer's Disease and Brain Insulin Resistance

This article discusses the overlapping aspects of Alzheimer’s disease, cancer, and brain insulin resistance from the perspective of neuronal cell cycle re-entry (CCR) , and consider strategies to exploit them for prevention or therapeutic intervention of Alzheimer’s disease.
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Elizabeth Sharlow's Research Focuses on Neglected Diseases

Sharlow's focus is on exploiting chemical biology approaches to understand signaling pathways that are critical for parasite, neuronal and tumor cell viability.
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