Jansen, Laura
Primary Appointment
Associate Professor, Neurology
Education
- MD/PhD, Pharmacology, Saint Louis University
- Medical Residency, Pediatric Neurology, Washington University
Contact Information
PO Box 800394
Cobb Hall
Charlottesville, VA 22908
Telephone: 434-924-5312
Email: laj2p@virginia.edu
Research Disciplines
Molecular Pharmacology
Research Interests
Pediatric Epilepsy, Human Brain Development, Inhibitory Neurotransmission
Research Description
My research interests are related to conditions that cause epilepsy and brain malformations in children. My lab uses a combination of biochemical, electrophysiological, and imaging techniques to analyze both human brain specimens and cell culture models. Current projects ongoing in the lab include: 1) Characterizing the development of GABAergic inhibition in the premature and neonatal brain, and determining the effect of conditions causing seizures on this development. 2) Identifying the consequences of abnormal PI3K/AKT pathway activity on neuronal signaling. 3) Determining the histopathologic and functional outcomes of genetic mutations that cause neurologic disease in children.