Neuroscience has emerged as a highly multi-disciplinary science with enduring mysteries. We are exploring many aspects of this discipline at the level of molecules, cells and circuits. Using a variety of experimental approaches, we hope to improve our understanding of neurophysiology as well as neuropathology.
Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.
Mechanisms of neuromodulation in central neurons
Circuit mechanisms of sleep and epilepsy
Neural control of blood pressure and respiration
Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.
Investigation of the neuronal circuits and epigenetic modifications involved in the control of food intake, impulsivity and novelty seeking behavior
Neural Circuits in Healthy and Diseased Brains
Other PSTG Faculty
Pathogenic mechanisms in Alzheimer's Disease and other neurodegenerative disorders
The Neurobiology of Energy Balance
Elucidating and Understanding the Mechanisms Underlying Nervous System Development
The Role of Diabetes in Cognitive Decline
Exploring new therapeutics avenues to treat Multiple Sclerosis.
Behavioral Pharmacology, Sex Differences, Animal Models of Addiction
Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.