Cellular Physiology

Because novel approaches to drug development require a new and comprehensive understanding of cellular organization and communication, the mechanisms by which cells transmit signals within and among cells is an area of emphasis within the Department. The Department of Pharmacology at the University of Virginia has a distinguished scientific history in the study of cellular signaling processes (signal transduction); two recent Nobel Laureates honored for their work deciphering pathways of cellular signaling conducted this work in the Pharmacology Department at the University of Virginia. Today, faculty of the Department of Pharmacology bring to bear a wide range of scientific approaches and technical methods to address fundamental questions of cellular signaling related to neural transmission, hormone and growth factor signaling, cell cycle regulation, neoplasia and regulation of gene expression.

Pharmacology Faculty

Douglas Bayliss

Bayliss, Douglas A.

Mechanisms of neuromodulation in central neurons

Mark Beenhakker

Beenhakker, Mark P.

Circuit mechanisms of sleep and epilepsy

Bimal Desai

Desai, Bimal N.

Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis

Thurl Harris

Harris, Thurl E

Molecular mechanisms controlling insulin signaling and fat synthesis.

Edward Perez-Reyes

Perez-Reyes, Edward

Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.

Other PSTG Faculty

Ilya Levental

Levental, Ilya

Composition, Biophysics and Physiology of Cellular Membranes

Bettina Winckler

Winckler, Bettina

Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.