Cardiovascular / Respiratory Biology
We aim to understand the molecular and physiological basis of the heart, lung and blood diseases. The related study of neuronal mechanisms that regulate respiration and blood pressure provides an integrated view of these vital processes. This understanding is leveraged to improve the diagnosis, treatment and prevention of cardiovascular and respiratory diseases.
Mechanisms of neuromodulation in central neurons
Cell signaling of protein kinases in development and disease
Neural control of blood pressure and respiration
Chemical Biology, Lipid Biochemistry, Medicinal Chemistry, and Mass Spectrometry
Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes
Chemical biology of sphingosine 1-phosphate
Regulation of transcription by nuclear hormone receptors, transcriptional control of metabolism and inflammation, small molecule approaches to drug discovery
Role of endogenous peptides in control of cardiorespiratory function
Other PSTG Faculty
Systems Genetics Approaches to Understand Cardiometabolic Traits
Translating our discoveries in the microcirculation to tangible benefits in patients.
Systems-biology approaches to cancer biology and virology.
Immune System Regulation of Cardiometabolic Disease
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease
Identify the calcium signaling abnormalities that lead to vascular dysfunction and blood pressure elevation in cardiovascular disorders